Is nitric oxide the forgotten nephroprotective treatment during cardiac surgery?
نویسندگان
چکیده
منابع مشابه
Effect of diabetes on nitric oxide metabolism during cardiac surgery.
The metabolism of nitric oxide (NO) during cardiac surgery is unclear. We studied the effect of diabetes on NO metabolism during cardiac surgery in 40 subjects (20 with diabetes and 20 without diabetes). The patients were randomized to receive an infusion of physiological saline or nitroglycerin (GTN) at 1 microg. kg(-1). min(-1) starting 10 min before the initiation of cardiopulmonary bypass a...
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Nitric oxide (NO) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. Recent evidences suggest that NO may act as an endocrine molecule. The aim of this review is considering available literature on endocrine roles of NO and/or its metabolites, i.e. nitrite and nitrate. Existing data suggest the idea that NO is a hormone that after production i...
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To the Editor: We read with interest the article by Karkouti et al.1 published in the March 2015 issue regarding a transfusion algorithm based on point-of-care coagulation tests in cardiac surgery. We wish to shed light on an issue that was not touched upon in the article but represents the first step in their algorithm and, without dispute, the first and most important single intervention in m...
متن کاملis nitric oxide a hormone?
nitric oxide (no) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. recent evidences suggest that no may act as an endocrine molecule. the aim of this review is considering available literature on endocrine roles of no and/or its metabolites, i.e. nitrite and nitrate. existing data suggest the idea that no is a hormone that after production i...
متن کاملHemolysis during cardiac surgery is associated with increased intravascular nitric oxide consumption and perioperative kidney and intestinal tissue damage
INTRODUCTION Acute kidney injury (AKI) and intestinal injury negatively impact patient outcome after cardiac surgery. Enhanced nitric oxide (NO) consumption due to intraoperative intravascular hemolysis, may play an important role in this setting. This study investigated the impact of hemolysis on plasma NO consumption, AKI, and intestinal tissue damage, after cardiac surgery. METHODS Hemolys...
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ژورنال
عنوان ژورنال: Annals of Intensive Care
سال: 2020
ISSN: 2110-5820
DOI: 10.1186/s13613-020-0631-7